Malignant mesothelioma in Singapore.

Malignant mesothelioma: experience at the Singapore General Hospital.

INTRODUCTION Malignant mesothelioma is a rare occupational disease in Singapore. There have been few reports of this condition in Singapore. We aim to describe the clinical characteristics, management and outcomes in a case series of 16 patients diagnosed in a teaching hospital in Singapore. MATERIALS AND METHODS A chart review of all cases of malignant mesothelioma diagnosed in our instituti...

Generalised pruritus and elevated levels of immunoglobulin E acting as biomarkers of a malignant peritoneal mesothelioma.

The Role of Immunohistochemistry Studies in Distinguishing Malignant Mesothelioma from Metastatic Lung Carcinoma in Malignant Pleural Effusion

Background and Objective: Early diagnosis of malignant pleural mesothelioma (MPM) is the key point of its treatment. The main problem is the precise diagnosis of mesothelioma and its differentiation from metastatic lung adenocarcinoma. Mesothelioma exhibits complex immunohistochemical characteristics. The aim of this study was to study hybrid immunohistochemistry in the differe...

Pemetrexed in the treatment of thoracic malignancies: a single centre experience in Singapore.

INTRODUCTION This study aimed to examine the efficacy and toxicity of pemetrexed in Singapore. METHODS We conducted a retrospective review of patients treated with pemetrexed between July 2005 and November 2007. RECIST was used to assess the efficacy independent of the treating physician's assessment, and NCI CTC-AE version 3.0 was used to describe adverse events. RESULTS 37 patients had no...

PRIMARY MALIGNANT PERICARDIAL MESOTHELIOMA

Primary malignant neoplasms of the pericardium are rare and are predominantly mesotheliomas, followed by benign localized fibrous mesothelioma, malignant fibrosarcoma, angiosarcoma and benign and malignant teratomas. 1 This article concerns an atypical presentation of this malignant tumor with symptoms and signs of pericardial effusion. This unusual feature was complete encasement of the h...